So there's this new medal game called Smiley Popper, which is essentially a remove tiles game on a 20x20 grid. Within 2 hours of it being released here on Newgrounds I did this (full game video, just under 10 minutes):

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That combo of blues, by the way, was worth 9,223,372,036,854,775,807 points, or 1 less than 2^63. All other points are incidental. Sadly, the NG scoreboard only stores up to 2^32 points, so my score will forever be relegated to the tomb of 2 billion point games, but at least I have video evidence of my actual performance.

Several hours later, because I felt like playing a short game before going to bed, I fired the game up again and did this (only the end, less than 2 minutes):

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That's 1,208,925,819,614,629,174,706,175 points for popping a group of 80 greens (2^80 - 1). A higher score is possible, but certainly not realistic; there's an E24 at the end of my score in the game. I thought I was done, but then I found out the website where the game was developed uses Mochi to save scores, which will actually save the full score rather than cutting off. So I played it again over there, and did this:

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That's 9,671,406,556,917,033,397,649,407 points in a single drop. The next highest score on that site is 2^21 points behind me, meaning nobody else has gotten a drop bigger than 2^62. Now I'm done.